Nothing is worse than AV trying to dig into mail databases and grab viruses. Also boxes that run functions such as email will need AV that is specifically tailored to that environment.

Tweaked to offer protection with minimal performance impact. My policy is that ALL windows boxes get AV installed on them (linux is different story). You then have to compare that against the risk of having your data stolen, servers potentially damaged, reputation hurt, time spent fixing, paranoia that you didn't clean it all up, etc.

you may not see the problem(s) right away. Servers are especially dangerous as they are usually on 24x7 and many of them don't get logged onto on a regular basis (i.e. This requires no user or admin intervention to spread. It has been a long time since I have seen a good worm that exploited a MS bug and could freely move from computer to computer. Antivirus software while installed on the windows servers do not understand the application and its infrastructure and you however still need to have them. As a result, the cost and efforts associated with a virus infection can be significantly reduced.I think the real argument for having AV on windows servers is Worms or other viruses that can spread without the need for a incompetent (or unlucky) admin. This robust solution enables enterprises to secure the entire server file system including compressed archives, distribute virus patterns to remove any viruses that get through, and help automate the damage cleanup process to resolve problems left by virus infections. Administrators can use one management console to centrally enforce, administer, and update malware protection on every server throughout an organization. ServerProtect scans and detects malware in real time and incorporates cleanup capabilities to help remove malicious code and repair system damage. Trend Micro™ ServerProtect™ delivers the industry’s most reliable virus, spyware and rootkit protection while simplifying and automating security operations on servers. More importantly, today’s sophisticated attacks can target multiple points on the network and leave unseen trails of damage and the potential for re-infection. Additionally, large organizations may have hundreds or thousands of individual server machines that require monitoring, configuration, and maintenance. Even from inside the network, users or applications without adequate protection can unintentionally upload infected files to the server, which can spread to other systems that access these files. Enterprise servers can be a vulnerable, centralized point of information exchange.

Windows server antimalware